SCAN-B MutationExplorer

Tidig förändring av epigenetisk-relaterad transkription i huntingtons

Results. Inositol-trisphosphate 3-kinase A gene (ITPKA), a kinase  5 Jan 2021 In contrast, ITPKA is expressed primarily in neurons, while ITPKC expression is restricted to glia (27). qPCR analysis of ITPKA, ITPKB, and ITPKC  In lung and breast cancer expression of ITPKA is stimulated by gene body methylation which  23 Feb 2021 GAPDH gene was the internal control for ITPKA. Primers for ITPKA was designed based on GenBank reference sequence (Genebank  Key Words: Human cumulus cell, gene expression, oocyte quality, pregnancy, live birth and HSD3B1) and the calcium-related genes (TRPM7, ITPKA,. PTHLH  suppresses expression of neuronal genes in nonneuronal tissues, regulates expression of ITPKA.

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Summaries for ITPKA gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL) About This Sectio Summary: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. 2017-08-01 Gene ID: Human(3706) Summary: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. The Parkinson’s disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release Daniel J. Apiccoa,b,1 , In contrast, ITPKA is expressed primarily in neurons, while ITPKC expression is restricted to glia (27). qPCR analysis of ITPKA, ITPKB, and ITPKC expression in primary mouse cor- ITPKA Gene inositol-trisphosphate 3-kinase A Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4.

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Curated assertions on the My Cancer Genome website are housed within a Knowledge Management System (KMS) created through a partnership with GenomOncology that serves as a warehouse of biomarker, disease, and drug ontologies; biomarker-driven cancer clinical trials; therapeutic, prognostic, and diagnostic assertions; and … The C-terminal part of ITPKB, namely residues 187 to 462, was 68% identical to ITPKA in amino acid sequence. Mapping By in situ hybridization, Erneux et al. (1992) mapped the ITPKB gene to 1q41-q43. Next-day shipping cDNA ORF clones derived from ITPKA inositol-trisphosphate 3-kinase A available at GenScript, starting from $99.00.

Gene Stat Angle Cell Pvalue Qvalue A1BG 1.07177295114858

1 RefSeq (NM) Transcript Type Coding Product Type Silencer® Select Availability. Made to Order.

RRO   Use the search box at the top right of all Ensembl views to search for a gene, phenotype, sequence Gene-based displays Gene: ITPKA ENSG00000137825. 24 May 2016 In silico analysis of The Cancer Genome Atlas data set was also performed. Results. Inositol-trisphosphate 3-kinase A gene (ITPKA), a kinase  5 Jan 2021 In contrast, ITPKA is expressed primarily in neurons, while ITPKC expression is restricted to glia (27).
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Mapping By in situ hybridization, Erneux et al. (1992) mapped the ITPKB gene to 1q41-q43. Plasmid ITPKA_3xmScarletI from Dr. Dorus Gadella's lab contains the insert ITPKA and is published in bioRxiv 160374 This plasmid is available through Addgene. ITPKA gene, which is located in 15q15, encodes a predicted 461 amino acid polypeptide. Under physiological conditions, ITPKA is only identified in neurons and testis [ 6 ].

The siRNA interferes with the expression of Itpka gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. Next-day shipping cDNA ORF clones derived from ITPKA inositol-trisphosphate 3-kinase A available at GenScript, starting from $99.00. Gene views which provide displays for data associated at the gene level such as orthologues, paralogues, regulatory regions and splice variants. This view is a gene level view. To access the transcript level displays select a Transcript ID in the table above and then navigate to the information you want using the menu at the left hand side of the page. dramatically down-regulated ITPKA expression in all OSCC cell lines examined.
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Taken together, CGIAR genebanks represent the largest  27 Oct 2020 A 35-gene expression profile (GEP) test that classifies melanocytic lesions into categories (benign, intermediate-risk and malignant), has  21 Aug 2020 Formalin Fixed Genes DNA Gene Sequence Genprice Antibodies Gentaur Cytokines IHC Fixed Slides Immuno Histo Chemistry Immunology  2020年5月15日 Research question Does double stimulation (DuoStim) affect cumulus cell gene expression in luteal-phase-derived oocytes? Design This  Rabbit polyclonal antibody raised against recombinant ITPKA.Hundratusentals antikroppar är tillgängliga hos VWR. Hitta din antikropp genom att selektera på  IP3KA siRNA (h), shRNA and Lentiviral Particle Gene Silencers are designed to knockdown gene expression of human IP3KA. Cited in 1 publications. proteins (a major isoform for each protein encoding gene).

Rattus norvegicus (Rat) Status. Reviewed-Annotation score: -Experimental evidence at protein level i. Function i Catalytic activity i. 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5 2016-09-01 2006-05-11 General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC.
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Anti-ITPKA Rabbit Polyclonal Antibody VWR

ITPKA has 3,320 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 82 datasets.

Gene Stat Angle Cell Pvalue Qvalue A1BG 0.588360560294644

The protein encoded by the ITPKB gene is one of 3 isoforms of Inositol-trisphosphate 3-kinase expressed in humans.

Predicted to localize to cytoplasm and nucleus. Orthologous to human ITPKA (inositol-trisphosphate 3-kinase A). ITPKA is expressed in a broad range of tumor types but shows limited expression in normal cells. In lung and breast cancer expression of ITPKA is stimulated by gene body methylation which increases with increasing malignancy of these tumors but is not detectable in the corresponding normal tissues. Gene: Itpka - ENSRNOG00000005284 - Rattus norvegicus (rat) General information. Ensembl ID: ENSRNOG00000005284: Name: Itpka: Description RefSeq summary [ITPKA] Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol Plasmid pCNL-N1_ITPKA from Dr. Yasushi Okada's lab contains the insert inositol triphosphate 3-kinase A and is published in Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4352-6. doi: 10.1073/pnas.1418468112.